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Alpha-1-Antitrypsin

Alpha 1-Antitrypsin is a protease inhibitor, with the role of protecting tissues from enzymes of inflammatory cells, especially neutrophil elastase. It is expressed in the liver and has a molecular weight of 52 kDa. In disease Alpha 1-antitrypsin deficiency is a hereditary disorder in which a deficiency of A1AT leads to a chronic uninhibited tissue breakdown, specifically effecting the lung tissue. It eventually leads to characteristic manifestations of pulmonary emphysema.

Abbreviation A1AT
Synonyms α1-antitrypsin, serum trypsin inhibitor, alpha-1 proteinase inhibitor
CAS No. 9041-92-3
Molecular Weight 52 kDa

Variants (Click plus sign to expand variant information)

  Variant Name Product Code Purity
+
 Alpha-1-Antichymotrypsin, ultra pure P159-0 Ultra Pure
 
Purity Ultra Pure
Specification > 99% pure
Source Human Serum
Presentation Lyophilized
Reconstitution Use of phosphate buffer, pH >7.0 containing 0.15M NaCl is recommended. To ensure full product recovery, it is advised that reconstitution is performed directly into supplied vial incorporating further washings with the reconstitution buffer.
Health and Safety Starting material tested for HIV 1 & 2 Antibodies, Hepatitis B Surface Antigen Hepatitic C Virus Antibodies and Hepatitis B Core Antibodies. No test can guarantee the absence of an infectious agent. Please handle as potentially hazardous.
Minimum Order 1 mg
Storage Temperature 2 - 8°C
Shipping Recommendation Cool Pack
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