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Insulin Like Growth Factor

Insulin-like growth factors (IGFs) play important roles in mammalian growth and development. They may also be involved in the development of cancers and atherosclerosis. IGF1 mediates many of the growth-promoting effects of growth hormone. IGF binding proteins bind to IGF’s. Raised circulating IGF binding protein-1 (IGF BP1) levels are found in subjects with severe pre eclampsia. IGF BP3 can inhibit cell proliferation by binding to, and inactivating IGF-1 and IGF-2. Binding of IGF-1 to IGF-BP5 has a controlling effect on the cellular action of IGF-1. It also prolongs the biological half-life of the IGF-1. IGF-1R strongly binds both IGF-1 and IGF-2.

Abbreviation IGF, IGF-BP3, IGF-BP4

Variants (Click plus sign to expand variant information)

  Variant Name Product Code Purity
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Insulin Like Growth Factor Binding Protein 1 P254-2 Highly Pure
 
Purity Highly Pure
Specification > 95% pure
Source Rec. From NSO cells
Presentation Lyophilized
Health and Safety Material is non-infectious
Minimum Order 100 µg
Storage Temperature < -15°C
Shipping Recommendation Dry Ice
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Insulin Like Growth Factor Binding Protein 4 P324-1A Highly Pure
 
Purity Highly Pure
Specification > 96% pure
Source Rec. From E.coli
Presentation Lyophilized
Reconstitution Reconstitute in deionised water > 100µg/ml. To ensure full product recovery, it is advised that reconstitution is performed directly into the supplied vial incorporating further washings with the reconstitution buffer. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Health and Safety Material is non-infectious
Minimum Order 100 µg
Storage Temperature < -15°C
Shipping Recommendation Cool Pack
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Insulin Like Growth Factor 1, highly pure P264-0 Highly Pure
 
Purity Highly Pure
Specification > 95% pure
Source Rec. From E.coli
Presentation Lyophilized
Reconstitution Reconstitute in deionised water > 100µg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Health and Safety Material is non-infectious
Minimum Order 1 mg
Storage Temperature < -15°C
Shipping Recommendation Cool Pack