Product Browser

Product

Kininogen

Human Kininogen is a coagulation protein involved in the early stages of intrinsic pathway activation. High molecular weight kininogen deficiency (or Fitzgerald factor deficiency) can cause prolongation of the partial thromboplastin time . Human kininogen is 626 amino acids long, and has a molecular weight of 88 to 120 kD (dependent on glycosylation). High Molecular Weight Kininogen is not enzymatically active, and only functions as a cofactor for the activation of kallikrein and Hageman factor. It is also necessary for the activation of factor XI by factor XII a. Kininogen is also a precursor of bradykinin; released through positive feedback by kallikrein. As an endogenous protein substrate for tissue kallikrein, Low Molecular Weight Kininogen is involved in blood pressure regulation.

Variants (Click plus sign to expand variant information)

  Variant Name Product Code Purity
+
 Kininogen - High Molecular Weight, highly pure P262-1 Highly Pure
 
Purity Highly Pure
Specification > 95% pure
Source Human Plasma
Presentation Acetate Buffer
Health and Safety Starting material tested for HIV 1 & 2 Antibodies, Hepatitis B Surface Antigen and Hepatitic C Virus Antibodies. No test can guarantee the absence of an infectious agent. Please handle as potentially hazardous.
Minimum Order 100 µg
Storage Temperature < -15°C
Shipping Recommendation Dry Ice
Buy from SunnyLab
+
 Kininogen - Low Molecular Weight, highly pure P261-1 Highly Pure
 
Purity Highly Pure
Specification > 95% pure
Source Human Plasma
Presentation Acetate Buffer
Health and Safety Starting material tested for HIV 1 & 2 Antibodies, Hepatitis B Surface Antigen and Hepatitis C Virus Antibodies. No test can guarantee the absence of an infectious agent. Please handle as potentially hazardous.
Minimum Order 100 µg
Storage Temperature < -15°C
Shipping Recommendation Dry Ice
Buy from SunnyLab