NGAL is a member of the lipocalin proteins family, expressed predominantly in neutrophils, but also kidney, prostate and epithelial tissues. The function of NGAL in the human body is not fully understood, however it is believed to act as an inate antibacterial factor.(1) It is upregulated in cells under stress from inflammation, bacterial infection, neoplastic conditions and renal disorders. NGAL is a new early marker for acute kidney injury. Levels rise rapidly after renal injury and have been used in a variety of clinical situations including intensive care, emergency medicine, renal transplantation and procedures involving the use of i.v. contrast media and other nephrotoxic agents. Studies have indicated that this marker has the greatest potential for the prediction and monitoring of acute renal injury following cardiac surgery.2 This potential has now been expanded upon, with development and commercialization of highly specific ELISA testing kits.
| Abbreviation | NGAL |
| Synonyms | Lipocalin 2 |
| Molecular Weight | 22 kDa |
| Variant Name | Product Code | Purity | |
|---|---|---|---|
+ |
Neutrophil Gelatinase Associated Lipocallin, highly pure | P722-1 | Highly Pure |
